In a competitive game, you sometimes rely on skilful throwing to win. You may rely on appropriate tactics.
But dang it, sometimes you can just use your physical advantages.
One example is stamina. If you have a slow handler defending you, and you have good stamina, start doing laps. Cut upfield, then cut downfield, cut up, cut down. No stopping or joining the stack. If they aren't smart enough to switch (and I find about 50% of the time they aren't), they will get exhausted marking you.
Then time your cut for a goal, or watch them make a throwing or catching error later in the point/next point.
When only a minority of players are doing a regular fitness program, and you are one of them, this is very do-able. Just be judicious in when you use this, and how often, or else in the next match you may be a step slower, and your next opposition will have the advantage.
Its usually been quite entertaining when I have seen it.